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Caerphilly Prospective Study

Datasets -
Variables -
Start Year
1979
End Year
2012
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Members

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Investigators Contacts
  • Professor Yoav Ben-Shlomo
    University of Bristol
  • Professor Yoav Ben-Shlomo
    University of Bristol

Design

Study design
Cohort
Follow Up
National Health Service (NHS) Registry and Office of National Statistics (ONS) are used for mortality follow-up. Hospital Episode Statistics (HES) and electronic health records are used for follow-up of non-fatal coronary and stroke events. Re-examinations of participants are done 4 times (phases II - V) approximately every 5 years after the baseline (phase I) and subjects were asked about all hospital admissions, particularly those for cardiovascular disease.
Supplementary Information

Deaths and cardiovascular events are followed up for the harmonized MORGAM data, see detailed information on follow-up procedures used for MORGAM data in the MORGAM e-publication.

Marker Paper

Caerphilly and Speedwell collaborative heart disease studies. The Caerphilly and Speedwell Collaborative Group. J Epidemiol Community Health. 1984 Sep;38(3):259-62. doi: 10.1136/jech.38.3.259.

PUBMED 6332166

Recruitment

Sources of Recruitment
  • Individuals

Number of participants

Number of participants
2,171
Number of participants with biosamples
1,500

Data Access

Availability of data and biosamples

Data
Biosamples
Other

Sector of research

Data Biosamples
Investigators from the public sector
Investigators from the private sector
Investigators from not-for-profit organization

Transfer

Data Biosamples
Can leave the study facility
Can leave the country

Description of the access procedures

Biosamples and local data available are described in the study webpage. An independent steering committee reviews all requests for collaboration, read more about collaborating in the study webpage.

For access to the harmonized MORGAM data from many MORGAM Centres, one should seek a collaboration with any of the Centre which can submit a publication proposal to the MORGAM/BiomarCaRE Steering Group.


Availability of access information

On the study website : http://www.bristol.ac.uk/population-health-scie...

By contacting the study representative

Yes
No
Not applicable
Don't know

Timeline

Caerphilly Study Cohort

Selection Criteria
Gender
men
Minimum age
55
Maximum age
69
Countries
  • United Kingdom
Territory
Caerphilly, a former mining town in South Wales, and outlying villages.
Ethnic Origin
Health Status

Recruitment

Sources of recruitment
  • General population
General Population
  • Selected sample
Supplementary Information

Number of participants

Number of participants
2,171
Number of participants with biosamples
1,500
Supplementary Information
Response rate to the Phase III survey was 70%.
Data Collection Events
# Name Description Start End
0 Caerphilly Study Phase I Initial baseline examination where participants completed the questionnaire, and had anthropometric measures, ECG and blood samples taken. They also completed food frequency questionnaire at home. ... 1979-07 1983-09
1 Caerphilly Study Phase II 1st re-examination (Phase II) of participants. Same tests as in phase I were undertaken in addition of audimetry test. This phase is not included in the harmonized MORGAM data. 1984-07 1989-04
2 Caerphilly Study Phase III Second re-examination (phase III) of participants that is used as a baseline in the MORGAM data (questionnaire and health examination). This phase is identified by the round 03 of the Cohort 21 ... 1989-05 1993-09
3 Caerphilly Study Phase IV 3rd re-examination (phase IV) of participants. Audiometry measured at phase II and cognitive function measured at phase III were repeated. Genomics are measured for this phase. This phase is not ... 1993-10 1997-02
4 Caerphilly Study Phase V Fourth re-examination of the participants. Same methods were used as in precedent phases. This phase is identified by the round 05 of the Cohort 21 of the UNK-CAE in the harmonized MORGAM data. ... 2002-05 2004-09
5 Caerphilly Study mortality and disease outcome follow-up in MORGAM data Follow-up for cardiovascular events and death in the harmonized MORGAM data, see the end-points followed up in [the MORGAM e-publication](https://www.thl.fi/publications/morgam/cohorts/full/uk/unk-... 1989-05 2012-02
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