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DAN-MONICA Study

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Datasets -
Variables -
Start Year
1982
Supplementary Information
The DAN-MONICA Study was conducted by the Copenhagen County Centre for Preventive Medicine, Glostrup Hospital, University of Copenhagen, Denmark. The study is also known as the Glostrup Population Studies and study of the Research Centre for Prevention and Health (RCPH).
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Members

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Investigators Contacts
  • Allan Linneberg
    Bispebjerg and Frederiksberg Hospital
  • Torben Jørgensen
    Bispebjerg and Frederiksberg Hospital

Design

Study design
Cohort
Follow Up
The cohorts were linked to the National Hospital Discharge Register, to the Causes of Death Register and to the Civil Registration System using the personal identification number.
Supplementary Information
Deaths, several cardiovascular events and type 2 diabetes are followed up for the harmonized MORGAM data, see detailed information on follow-up procedures in the MORGAM e-publication. Cohort 01 has two re-examination rounds after the baseline.

Marker Paper

Gerdes, Bronnum-Hansen H, Osler M. Trends in Lifestyle Coronary Risk Factors in the Danish MONICA Population 1982-1992. Public Health 116, no. 2 (2002): 81-88.

Osler M, Linneberg A, Glümer C, Jørgensen T. The cohorts at the Research Centre for Prevention and Health, formerly 'The Glostrup Population Studies'. Int J Epidemiol. 2011 Jun;40(3):602-10. doi: 10.1093/ije/dyq041.

Jørgensen T, Borch-Johnsen K, Thomsen TF, Ibsen H, Glümer C, Pisinger C. A randomized non-pharmacological intervention study for prevention of ischaemic heart disease: baseline results Inter99. Eur J Cardiovasc Prev Rehabil. 2003 Oct;10(5):377-86. doi: 10.1097/01.hjr.0000096541.30533.82.

Thuesen BH, Cerqueira C, Aadahl M, Ebstrup JF, Toft U, Thyssen JP, Fenger RV, Hersoug LG, Elberling J, Pedersen O, Hansen T, Johansen JD, Jørgensen T, Linneberg A. Cohort Profile: the Health2006 cohort, research centre for prevention and health. Int J Epidemiol. 2014 Apr;43(2):568-75. doi: 10.1093/ije/dyt009.

PUBMED ?term=11961675%5BPMID%5D+OR+20338891%5BPMID%5D+OR+14663300%5BPMID%5D+OR+23615486%5BPMID%5D

Recruitment

Sources of Recruitment
  • Individuals

Number of participants

Number of participants
20,500
Number of participants with biosamples
20,000
Supplementary Information

Data Access

Availability of data and biosamples

Data
Biosamples
Other

Description of the access procedures

The access to use the Danish National Archives’ survey data is described in the Rigsarkivet webpage. Find and order data from the Danish National Archives’ collection of survey data (search e.g. "MONICA").

For access to the harmonized MORGAM data from many MORGAM Centres, one should seek a collaboration with any of the Centre which can submit a publication proposal to the MORGAM/BiomarCaRE Steering Group.


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No
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Timeline

Populations

Selection Criteria
Minimum age
30
Maximum age
70
Countries
  • Denmark
Territory
Eleven municipalities in the western part of Greater Copenhagen Area.
Ethnic Origin
Health Status
Supplementary Information
Random sample was drawn from those that were born in 1914, 1922, 1932, 1942 or 1952. The age of the persons at the baseline was about 30, 40, 50, 60 or 70 years.

Recruitment

Sources of recruitment
  • General population
General Population
  • Selected sample
Supplementary Information

Number of participants

Number of participants
4,052
Number of participants with biosamples
3,785
Supplementary Information
Response rate to the baseline survey was 79%. The first re-examination was participated by 81% of the cohort, and the second re-examination by 70%. 102 new persons entered the cohort at round 03. Total number of persons in the case-cohort set (selection 58) is 2615.
Data Collection Events
# Name Description Start End
0 DAN-MONICA Cohort 01 Baseline Baseline examination (questionnaire and health examination) This baseline data is identified by Round number 01 of the Cohort 01 (DEN-GLO) in the harmonized MORGAM data. Biomarkers have been ... 1982-11 1985-02
1 DAN-MONICA Cohort 01 Round 02 First re-examination (questionnaire and health examination) of the cohort. This re-examination data is identified by Round number 02 of the Cohort 01 (DEN-GLO) in the harmonized MORGAM data. ... 1987-12 1988-12
2 DAN-MONICA Cohort 01 Round 03 Second re-examination (questionnaire and health examination) of the cohort. This re-examination data is identified by Round number 03 of the Cohort 01 (DEN-GLO) in the harmonized MORGAM ... 1993-06 1994-12
3 DAN-MONICA Cohort 01 Mortality and disease outcome follow-up in MORGAM data Follow-up for cardiovascular events, type 2 diabetes and death in the harmonized MORGAM data, see the end-points followed up in the [MORGAM e-publication](https://www.thl.fi/publications/morgam/coh... 1982-11 2010-12
Selection Criteria
Minimum age
30
Maximum age
60
Countries
  • Denmark
Territory
Eleven municipalities in the western part of Greater Copenhagen Area.
Ethnic Origin
Health Status
Supplementary Information
Random sample was drawn from those that were born in 1926, 1936, 1946 or 1956. The age of the persons at the baseline was about 30, 40, 50 or 60 years.

Recruitment

Sources of recruitment
  • General population
General Population
  • Selected sample
Supplementary Information

Number of participants

Number of participants
1,504
Number of participants with biosamples
1,504
Supplementary Information
Response rate to the baseline survey was 75%. Total number of persons in the case-cohort set (selection 58) is 757.
Data Collection Events
# Name Description Start End
0 DAN-MONICA Cohort 02 Baseline Baseline examination (questionnaire and health examination) Biomarkers have been measured in the BiomarCaRE Project. 1986-08 1987-04
1 DAN-MONICA Cohort 02 Mortality and disease outcome follow-up in MORGAM data Follow-up for cardiovascular events, type 2 diabetes and death in the harmonized MORGAM data, see the end-points followed up in the [MORGAM e-publication](https://www.thl.fi/publications/morgam/coh... 1986-08 2010-12
Selection Criteria
Minimum age
30
Maximum age
70
Countries
  • Denmark
Territory
Eleven municipalities in the western part of Greater Copenhagen Area.
Ethnic Origin
Health Status
Supplementary Information
Random sample was drawn from those that were born in 1921, 1931, 1941, 1951 or 1961. The age of the persons at the baseline was about 30, 40, 50, 60 or 70 years.

Recruitment

Sources of recruitment
  • General population
General Population
  • Selected sample
Supplementary Information

Number of participants

Number of participants
2,026
Number of participants with biosamples
2,026
Supplementary Information
Response rate to the baseline survey was 74%. Total number of persons in the case-cohort set (selection 58) is 992. Total number of persons in the case-cohort set (selection 28) is 264.
Data Collection Events
# Name Description Start End
0 DAN-MONICA Cohort 03 Baseline Baseline examination (questionnaire and health examination) Biomarkers have been measured in the BiomarCaRE Project. 1991-02 1992-05
1 DAN-MONICA Cohort 03 Mortality and disease outcome follow-up in MORGAM data Follow-up for cardiovascular events, type 2 diabetes and death in the harmonized MORGAM data, see the end-points followed up in the [MORGAM e-publication](https://www.thl.fi/publications/morgam/coh... 1991-02 2010-12
Selection Criteria
Minimum age
30
Maximum age
60
Countries
  • Denmark
Territory
11 municipalities in the south-western part of Copenhagen County
Ethnic Origin
Health Status
Supplementary Information
The study cohort was divided randomly into three groups: two intervention groups and a control group. group A (the high-intensity group that was offered lifestyle discussion and participation in smoking cessation or diet-exercise groups), group B (the low-intensity group that were only offered a lifestyle interview, and had to consult their own doctor if they wanted more support) and group C (the background population which formed the control group and which was not affected).

Recruitment

Sources of recruitment
  • General population
General Population
  • Selected sample
Supplementary Information

Number of participants

Number of participants
13,016
Number of participants with biosamples
Supplementary Information
13016 randomly selected people (from 61301 individuals) were invited to a health examination and lifestyle interview. 52.5% of the people in the intervention groups participated in the first examination.
Data Collection Events
# Name Description Start End
0 Inter99 Baseline Baseline examination (questionnaire and health examination) Both intervention groups completed questionnaires, had a health examination and a lifestyle interview. People in the high-intensity ... 1999-03 2001-01
1 Inter99 1-year follow-up All high-risk participants in the intervention group were re-invited 1 year after baseline for a health examination, completion of a questionnaire, risk assessment and individual and group-based ... 2000-05 2002-09
2 Inter99 3-year follow-up All high-risk participants in the intervention group were re-invited 3 years after baseline for a health examination, completion of a questionnaire, risk assessment and individual and group-based ... 2002-04 2004-07
3 Inter99 5-year follow-up Five years after baseline, all participants eligible at baseline were re-invited for a screening, individual counselling and a plan for maintenance. The control group was followed by questionnaire ... 2004-03 2006-06
4 Inter99 10-year follow-up questionnaire Ten years after baseline, all survived participants eligible at baseline received post-intervention follow-up questionnaires. The questionnaire consists of questions on lifestyle, motivation to ... 2009-03 2011-01
5 Inter99 20-year follow-up 20 years after the baseline, all survived participants were invited to the re-examination (health examination and questionnaire). Participants are offered to take part in some additional studies: ... 2021
Selection Criteria
Minimum age
18
Maximum age
69
Countries
  • Denmark
Territory
1 municipalities in the south-western part of the greater Copenhagen area
Ethnic Origin
Health Status
Other criteria
Inclusion criteria was Danish citizenship and born in Denmark. Pregnant women were excluded.

Recruitment

Sources of recruitment
  • General population
General Population
  • Selected sample
Supplementary Information

Number of participants

Number of participants
3,471
Number of participants with biosamples
3,400
Supplementary Information
The participation rate was 44.7% to the health examination. Response rate to the re-examination was 68.6%.
Data Collection Events
# Name Description Start End
0 Health2006 Baseline Baseline examination (questionnaire and health examination). Two questionnaires were answered by all participants: a main questionnaire on lifestyle factors and general health and a supplementary ... 2006-06 2008-06
1 Health2006 5-year follow-up All participants are invited 5-year follow-up examination including essentially the same study protocol as in the baseline. In addition, the national registers will be used to follow the ... 2011-11 2012-11
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